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Gene-cutting system may play second role as a genetic dimmer switch – News-Medical.net

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting…

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In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 — as a genetic dimmer switch for CRISPR-Cas9 genes. Its role of dialing down or dimming CRISPR-Cas9 activity may help scientists develop new ways to genetically engineer cells for research purposes.
A summary of the findings was published Jan. 8 in Cell.
First identified in the genome of gut bacteria in 1987, CRISPR-Cas9…

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