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Developing a COVID-19 vaccine using inactivated E. coli – News-Medical.Net

A team of researchers inactivated whole-cell E.coli with a reduced genome and utilized this to express coronavirus-specific fusion peptides, demonstrating a potent…

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Inactivated whole-cell vaccines, also known as ‘killed vaccines,’ are amongst the most traditionally employed varieties of vaccine, having been developed against a wide range of pathogens, including cholera and E. coli.
In a new study, released as a preprint on the bioRxiv* server, a team of researchers inactivated whole-cell E.coli with a reduced genome and utilized this to express coronavirus-specific fusion peptides, demonstrating a potent anamnestic response.
Designing the vaccine
Gram-negative…

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