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Study: Inhibition of TLK protein stimulates the innate immune system – News-Medical.Net

Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication.

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Tousled-like kinases (TLKs) are a potential therapeutic target for cancer treatment due to their central role in DNA repair and replication.
The latest work by IRB Barcelona’s Genomic Instability and Cancer Laboratory, led by Travis H. Stracker, concludes that TLK inhibition activates the innate immune system, a very important factor in the response to cancer.
We believe the TLKs are promising targets for cancer therapy and want to understand more about how they work and how cells respond to t…

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