Health
Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor – News-Medical.Net
In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.
In a new bioRxiv study, a multinational group of authors identified a novel, primate-specific isoform of angiotensin-converting enzyme 2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types by interferons and viruses instead of ACE2. This finding has substantial implications for our understanding of coronavirus disease (COVID-19) pathology.
Figure 1. dACE2 is a novel primate-specific and virally-induced isoform of ACE2.
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