Health
In Pancreatic Cancer, New Biomarker May Predict Benefit of Tumor-Penetrating Peptide – Genetic Engineering & Biotechnology News
Study of pancreatic cancer identified biomarker that may indicate which patients would respond best to combination therapies incorporating a tumor-penetrating peptide….
Hunkered behind a dense layer of fibrotic tissue, pancreatic tumors stubbornly resist the delivery of therapeutic molecules. Yet this barrier, this desmoplastic tumor tissue, can be penetrated by iRGD, a nine-amino-acid cyclic peptide. In experiments with models of pancreatic cancer, specifically, mouse models and organoids, iRGD was found to penetrate tumors via a molecular pathway mediated by 5 integrin, a protein that is produced by carcinoma-associated fibroblasts (CAFs). This newfound role…
-
General14 hours agoChina and Philippines trade blame over latest South China Sea clash
-
Noosa News23 hours agoConfusion over licensing and access to hunting grounds under WA’s strict gun laws
-
General14 hours agoOf saints and sinners | The Spectator Australia
-
Noosa News19 hours agoBrisbane rising on global rankings, but still behind southern capitals