Health
O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines – News-Medical.Net
The mapping of O-glycosites requires instruments that can support electron transfer dissociation (ETD) fragmentation. In a new study published on the bioRxiv preprint…
Sites of O-glycosylation on the spike protein were near N-glycosites, suggesting O-glycans complement N-glycans’ effect in immune shielding.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the COVID-19 pandemic, has some characteristics that were not seen before in human coronaviruses, such as mutation on the receptor-binding domain (RBD) for high affinity to the human angiotensin-converting enzyme 2 (ACE2) and presence of a furin cleavage site between the two subunits…
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