SARS-CoV-2 nucleoprotein increases infectivity of spike-based pseudoviruses – News-Medical.Net

In a recent study conducted at the Indian Institute of Science Education and Research, India, a team of scientists screened specific genes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to identify factors that may contribute to viral infectivity.
Their findings suggest that SARS-CoV-2 nucleoprotein significantly increases the infectivity of spike-pseudotyped lentiviral particles, making the particles less susceptible to soluble angiotensin-converting enzyme 2 (ACE2)-mediated neutralization….

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