Health
Do antidepressants help back pain and osteoarthritis – News – The University of Sydney
Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering…
About the study:
The study was a systematic review and meta-analysis that included 33 randomised controlled trials with more than 5,000 participants with low back or neck pain, sciatica, or hip or knee osteoarthritis.
The trials tested six classes of antidepressants including serotonin-noradrenaline reuptake inhibitors (SNRIs) and tricyclic antidepressants.
The study set a difference of 10 points on a 0-100 scale for pain as the smallest worthwhile difference between groups, which is a common threshold…
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