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Cell membranes in super resolution – Phys.org

Expansion microscopy (ExM) enables the imaging of cells and their components with a spatial resolution far below 200 nanometres. For this purpose, the proteins…

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Expansion microscopy (ExM) enables the imaging of cells and their components with a spatial resolution far below 200 nanometres. For this purpose, the proteins of the sample under investigation are cross-linked into a swellable polymer. Once the interactions between the molecules have been destroyed, the samples can be expanded many times over with water. This allows detailed insights into their structures.
“This method was previously limited to proteins. In the journal Nature Communications we…

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