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Furin cleavage site of SARS-CoV-2 spike glycoprotein enhances viral replication in the lungs – News-Medical.Net

In a new bioRxiv* preprint paper, researchers from the Imperial College London, King’s College London, and the University of Bristol in the United Kingdom show …

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In a new bioRxiv* preprint paper, researchers from the Imperial College London, King’s College London, and the University of Bristol in the United Kingdom show that the furin cleavage site of SARS-CoV-2 spike glycoprotein represents a key determinant for transmission among humans, as it substantially facilitates replication in airway cells – opening the door for the development of novel therapeutics.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses enter …

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