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Adaptations found in RNA secondary structure in genes of two proteins of SARS-CoV-2 – News-Medical.Net

To investigate mutations in coronaviruses, a new study by scientists at Duke University and published on the preprint server bioRxiv, used a computational methodology, adaptiPhy, which identifies extra nucleotide substitutions in certain parts of the viral ge…

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Modeling indicates that secondary structures of RNA in the genes encoding the Nsp4 and Nsp16 proteins of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are different from other related coronavirus species, and this may affect some viral molecular processes.
With the dramatic spread of COVID-19 caused by the SARS-CoV-2 coronavirus, there has been a push to understand how a virus can infect new hosts and what makes it different from other coronaviruses.
One way of doing this is…

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