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Researchers develop new strategy to mimic heart-regenerating effects of cardiac cell transplants – News-Medical.Net

Ling Gao and colleagues have developed a strategy that uses exosomes – tiny membrane-bound sacs secreted by cells – to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants.

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Reviewed by Emily Henderson, B.Sc.Sep 17 2020
Ling Gao and colleagues have developed a strategy that uses exosomes – tiny membrane-bound sacs secreted by cells – to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants.
Their approach, which accelerated recovery from heart attack in pigs, could address issues with safety and effectiveness that have prevented whole-cell heart therapies from reaching clinical ado…

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