Health
PARP enzymes can bring two broken DNA ends together, shows study – News-Medical.net
Scientists at St. Jude Children’s Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together.
Reviewed by Emily Henderson, B.Sc.Sep 16 2020
Scientists at St. Jude Children’s Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together.
The study also provides insight into the mechanisms that underlie PARP activation and the catalytic cycle, which may aid in understanding resistance to cancer drugs that inhibit PARP. The work appears as an advance online publicati…
-
Noosa News20 hours agoQueensland teachers strike for second time this year after rejecting 8 per cent wage rise
-
General20 hours agoVictorian government blocked fire service from pursuing US giant over PFAS contamination
-
General24 hours agoXi Jinping tells Donald Trump Taiwan’s ‘return to China’ is key to international post-war order
-
General24 hours agoLabor path to pass nature laws in last week narrows