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Why cancer cells waste so much energy – MIT News

MIT biologists have found a possible explanation for the Warburg effect, first seen in cancer cells in the 1920s. They found cancer cells use fermentation, an inefficient…

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In the 1920s, German chemist Otto Warburg discovered that cancer cells dont metabolize sugar the same way that healthy cells usually do. Since then, scientists have tried to figure out why cancer cells use this alternative pathway, which is much less efficient.
MIT biologists have now found a possible answer to this longstanding question. In a study appearing in Molecular Cell, they showed that this metabolic pathway, known as fermentation, helps cells to regenerate large quantities of a molecule…

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