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When feeling the pinch, nuclei instigate cells to escape crowded spaces – Phys.org

The threat of serious deformation triggers a rapid escape reflex that enables cells to move away and squeeze out from tight spaces or crowded tissues.

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The threat of serious deformation triggers a rapid escape reflex that enables cells to move away and squeeze out from tight spaces or crowded tissues.
In a new study published today in the journal Science, researchers reveal that squeezing a cell to the point where its nucleus starts to stretch triggers the activation of motor proteins which in turn transform the cell’s cytoskeleton so that it can flee a packed environment.
Each cell has a nucleus, and each nucleus has a membrane that separate…

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