Science
When antibodies mislead: the quest for validation – Nature.com
Research antibodies don’t always do what it says on the tin. Test for true signals before you start your experiment.
Research antibodies are designed to recognize and bind to specific proteins according to their shape and chemical properties.Credit: Adapted from Molekuul/SPL
Commercial antibodies are commonplace in biology laboratories. Researchers use these giant Y-shaped proteins to detect specific molecules in cells, tissues and test tubes. But sometimes the proteins detect other molecules, too or even instead. When that happens, confusion can snowball.
Consider the gene CR9ORF72. Its often mutated in peo…
-
Noosa News19 hours agoBrisbane’s original 1979 electric trains take one last journey
-
Noosa News11 hours agoRainbow Beach surfer’s untold 7/7 story
-
General24 hours agoNRL live updates: Canberra Raiders vs St George Illawarra Dragons, North Queensland Cowboys vs Melbourne Storm
-
General24 hours agoWA road toll hits decade high as five people killed in 24 hours