What are Morpholinos? – News-Medical.net

A morpholino is a synthetic oligomer molecule that contains DNA bases on a methylene morpholine backbone, hence the naming convention: morpholine oligomer.
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They are used in biological research to modify or eliminate the expression of a gene in vitro, though have also been applied in vivo by modification of the molecule to allow better cell membrane penetration.
Morpholinos have been utilized to generate gene knockout specimens and thereby produce novel…

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