Science
We discovered a missing gene fragment that’s shedding new light on how males develop – Micky News
It’s one of the most important genes in biology: “Sry”, the gene that makes males male. The development of the sexes is a crucial step in sexual reproduct

Today in the journal Science, my international collaborators and I report the surprise discovery of an entirely new part of the Sry gene in mice a part we had no idea existed.
I co-discovered Sry in 1990. It is the gene on the Y (male) chromosome that leads to the development of male characteristics in mice, humans, and most other mammals. Since then, Sry has been the subject of intense study worldwide because of its fundamental role in mammalian biology.
We have come to understand, in some de…
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