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Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis – News-Medical.Net

The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials…

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Reviewed by Emily Henderson, B.Sc.Oct 8 2020
The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible are reviewed in the peer-reviewed journal Human Gene Therapy.
Treating CF by delivering mRNA that encodes CFTR has the potential to work in any CF patient, independent of the underlying mutation. Another potential treatment is …

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