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Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer – Science Advances

CD4 T cells have been implicated in cancer immunity for their helper functions. Moreover, their direct cytotoxic potential has been shown in some patients with…

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INTRODUCTION
Antigen-driven activation of naïve CD4 T cell precursors leads to their expansion and differentiation into a wide spectrum of functionally defined subsets (1). The diverse functional polarization of CD4 T cells

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