Health
The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing – Science Advances
Sunlight-associated melanomas carry a unique C-to-T mutation signature. UVB radiation induces cyclobutane pyrimidine dimers (CPDs)…
INTRODUCTION
Cancer genome sequencing has identified millions of somatic mutations in different types of human cancer (14), in some cases pointing to a potential origin of these mutations. Cancers linked to environmental exposures show tumor-specific mutational…
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