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The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing – Science Advances

Sunlight-associated melanomas carry a unique C-to-T mutation signature. UVB radiation induces cyclobutane pyrimidine dimers (CPDs)…

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INTRODUCTION
Cancer genome sequencing has identified millions of somatic mutations in different types of human cancer (14), in some cases pointing to a potential origin of these mutations. Cancers linked to environmental exposures show tumor-specific mutational…

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