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The evolution of single amyloid fibrils into microcrystals – Phys.org

Amyloids refer to abnormal fibrous extracellular and proteinaceous deposits found in organs and tissues that form insoluble constructs that are resistant to degradation….

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Amyloids refer to abnormal fibrous extracellular and proteinaceous deposits found in organs and tissues that form insoluble constructs that are resistant to degradation. Their formation can accompany disease, where each disease is characterized by a specific protein or peptide aggregate. The nanomechanical properties of amyloid fibrils and nanocrystals depend on their secondary and quaternary structure and intermolecular geometry. Scientists have used advanced imaging methods including atomic force…

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