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Study suggests a role for the hypothalamus in genetic susceptibility to IBD – News-Medical.Net

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children’s Hospital of Philadelphia…

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Reviewed by Emily Henderson, B.Sc.Oct 29 2020
Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children’s Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression. The researchers went on to implicate new genes involved in IBD risk that are enriched in both derived hypothalamic neurons, from a part of the brain that has…

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