Science
Study shows the mechanism how loss of de-N-glycosylation enzyme causes ill effect – EurekAlert
Loss-of-mutations in NGLY1, an enzyme that removes sugar chains, cause a multisystem developmental disorder called NGLY1 deficiency….
IMAGE: A schematic model of the mechanism of proteasome dysfunction by FBS2 in NGLY1 deficiency.
FBS2 induces cellular toxicity in the absence of NGLY by two steps. First, FBS2 ubiquitinates misfolded glycoprotein…
view more
Credit: TMIMS
Peptide: N-glycanase…
Continue Reading
-
General23 hours agoAustralia’s native flora emerges as an increasingly popular muse for bonsai hobbyists
-
Noosa News21 hours agoFears for the future of retro Chinese dining after blaze guts Sundoo in Townsville
-
General21 hours agoWA puppy farming laws see pet store crackdown in bid to stop unethical breeding
-
General17 hours agoFears super tax rise for rich will whack housing market