Science
Study resolves long-running controversy over critical step in gene silencing – Phys.org
A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH)….
A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH). Their findings, reported in Nature Structural and Molecular Biology, also explain certain mysteries about the behavior of this protein, known as Polycomb repressive complex 2 (PRC2).
PRC2 helps regulate whether genes are active (“on) or silent (“off”). PRC2’s role in gene silencing is critical throughout the lifespan, from embryo formation…
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