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Study identifies potential drug targets for developing new cancer immunotherapies – News-Medical.Net

A study has revealed that tumours can evade the immune system by telling immune cells to produce immunosuppressive steroids.

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A study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids.
Researchers from the Wellcome Sanger Institute, Department of Pathology, University of Cambridge, and MRC Cancer Unit, discovered that immune T cells from mouse skin and breast tumors secrete steroids, and that preventing this steroid production reduced growth of tumors in mice.
The study found that either removing a key steroid-producing gene, or switching it off with a …

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