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Study identifies mechanism behind SARS-CoV-2 fusion of host cells – News-Medical.Net

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the fusion of the spike protein to nearby healthy cells. New research…

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The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the fusion of the spike protein to nearby healthy cells. New research by German researchers sheds light on how this happens.
Sequential binding of two short amphipathic helices allows the SARS-CoV-2 fusion peptide to rapidly insert itself into the target membrane. They also found membrane fusion required strong anchoring made possible through double attachment and a conserved disulfide bridge.
The findings…

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