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Study elucidates the mode of action of SGLT2 inhibitors in diabetes – News-Medical.Net
Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown.
Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown. In a study conducted by a research group led by Peter Wolf, Martin Krssak and Michael Krebs from MedUni Vienna’s Department of Medicine III, magnetic resonance spectroscopy (MRS) was used to show that there is a direct correlation between the elimination of glucose via the kidneys and new glucose production in the liver.
A single dose of the SGLT-2 inhibitor dapagliflozin gives rise…
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