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Strategy identified to enhance activity of CAR T-cells against breast cancer – BioPharma-Reporter.com

A new study suggests that CAR T-cells, which are already used to treat certain blood cancers, may also be successful against solid tumors if combined with other…

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The findings, published in the Journal of Experimental Medicine (JEM), indicate that activating an immune signaling pathway best known for fighting viral and bacterial infections could boost the ability of genetically engineered T cells to eradicate breast cancer in mice.
The study was led by Jonathan S Serody, the Elizabeth Thomas professor of medicine, microbiology, and immunology and director of the cellular therapy program at the University of North Carolina School of Medicine. 
Chimeric antigen…

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