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Stem cell study illuminates the cause of a devastating inherited heart disorder – EurekAlert

Penn Medicine scientists have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM)– one of multiple congenital disorders caused…

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PHILADELPHIA–Scientists in the Perelman School of Medicine at the University of Pennsylvania have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM), an often-fatal heart disorder.
This inherited form of DCM — which affects at least several thousand people in the United States at any one time and often causes sudden death or progressive heart failure — is one of multiple congenital disorders known to be caused by inherited mutations in a gene called LMNA. The…

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