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Small molecule, big potential for treating prostate cancer – MIT News

A team of researchers led by MIT professor Angela Koehler identified a CDK9 inhibitor that could be developed into a treatment for castration-resistant prostate…

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Prostate cancer growth is often driven by male sex hormones called androgens. Hormone therapy is commonly administered to lower the level of androgens in the body, but relapse is common when the cancer cells develop resistance to these therapies.
A multidisciplinary team of cancer researchers led by Angela Koehler, the Samuel A. Goldblith Career Development Professor in Applied Biology and a member of MITs Koch Institute for Integrative Cancer Research, has identified a small molecule that can selectively…

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