Science
Skeletal muscle development and regeneration mechanisms vary by gender – EurekAlert
（上）単離培養した単一筋繊維の周囲で筋幹細胞が増殖する様子
（下）scKOマウスでは細胞死が増加し、ニッシェ関連遺伝子の発現が低下、細胞老化関連遺伝子の発現が増加する。
IMAGE:
- ERβ controls muscle growth in young female mice
- ERβ is essential for muscle regeneration in female mice
- Inactivation of ERβ causes an increase in apoptosis
- ERβ is required for satellite cell population expansion
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view more Credit: Associate Professor Yusuke Ono
Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormali…
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