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Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis – Science Advances
We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells from 32 IPF, 28 smoker and nonsmoker controls, and 18 chronic obstructive pulmonary disease (COPD) lungs. Among epithelial cel…
RESULTS
We profiled 312,928 cells from distal lung parenchyma samples obtained from 32 IPF lungs (45 libraries yielding 147,169 cells), 18 chronic obstructive pulmonary disease (COPD) lungs (24 libr…
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