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Signaling Pathway in Blood Vessels Used by Neurons Aids Cancer Metastasis – Clinical OMICs News

The researchers discovered that breast and lung cancer cells use a mechanism to persuade blood-vessel cells into making and releasing the gene Slit2 to help the…

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Researchers at Rockefeller University have discovered that cancer cells enlist nearby blood vessels to gain access to a signaling pathway used by neurons, allowing them to escape into the bloodstream and metastasize.
Their findings, Tumoral activation of TLR3SLIT2 axis in endothelium drives metastasis, is published in Nature and led by Sohail Tavazoie M.D., Ph.D., the Leon Hess professor at Rockefeller University.
Previously, scientists in Tavazoies lab observed that tumors that eventually met…

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