Shedding new light on the origin of metastases – Medical Xpress

Before an effective treatment can be devised, researchers have to understand the specific effect of an anti-cancer substance on the cell type, or even the cell, that produces metastases in the enormous cellular heterogeneity of tumors. A team from the University of Geneva (UNIGE) used a pioneering technique called spiked-scRNAseq that links the transcriptomic to single cell metastatic phenotypes of colon cancer tumor cells. The importance of the VSIG1 gene involved in intercellular interactions…

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