Health
Shattered Chromosomes Help Create Drug-Resistant Cancer Cells – Forbes
Tumor cells can amplify genes for resistance to anti-cancer drugs by shattering chromosomes.
Shattered DNA double helix (for illustrative purposes only).
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Researchers have found that cancer cells contain shattered chromosomes that can allow a tumor to become more aggressive and help it resist chemotherapy drugs.
Cancers evolve over several steps, and one of the earliest occurs when mutations create a tumor a group of abnormal cells. A mutation can involve anything from changing a single letter in DNA to rearranging an entire chromosome.
The most extreme rearrangement is to shatter…
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