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Severe SARS‐CoV‐2 patients develop a higher specific T‐cell response – Wiley

We quantified IFNg‐secreting T cells reactive against the M, N and S viral SARS‐CoV‐2 proteins using a standardized enzyme‐linked immunospot assay in 60 patients….

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Introduction
Severe acute respiratory syndrome coronavirus 2 (SARSCoV2) has spread rapidly worldwide. A large majority of SARSCoV2 patients, reportedly up to 60% in a highly confined population, remain asymptomatic.1 A few patients will need hospitalisation for moderate symptoms related to pneumonia but their requirement for oxygen therapy is low.2 The most severely affected patients, who require intensive care unit admission, develop acute respiratory distress syndrome at about 710 days after symptom…

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