Scientists knock out squid gene for 1st time: study – China.org.cn

CHICAGO, Aug. 2 (Xinhua) — A research team at the Marine Biological Laboratory (MBL) affiliated to the University of Chicago (UChicago) has achieved the first gene knockout in a cephalopod using the squid Doryteuthis pealeii.
The team used CRISPR-Cas9 genome editing to knock out a pigmentation gene in squid embryos, which eliminated pigmentation in the eye and in skin cells, or chromatophores, with high efficiency.
“CRISPR-Cas9 worked really well in Doryteuthis; it was surprisingly efficient,…

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