Science
Scientists develop first drug-like compounds to inhibit elusive cancer-linked enzymes – Phys.org
A team of scientists from the University of Michigan Rogel Cancer Center has developed the first drug-like compounds to inhibit a key family of enzymes whose malfunction is associated with several types of cancer, including an aggressive form of childhood leu…
A team of scientists from the University of Michigan Rogel Cancer Center has developed the first drug-like compounds to inhibit a key family of enzymes whose malfunction is associated with several types of cancer, including an aggressive form of childhood leukemia.
The enzymesknown as the nuclear receptor-binding SET domain (NSD) family of histone methyltransferaseshave long been an attractive drug target, but efforts to attack them have previously proved elusive because the shape of the bindin…
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