Scientists create ON-OFF Switches to Control CAR T cell activity – Newswise

• CAR T cells are a breakthrough class of effective but often toxic cancer therapies
• To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug 

Newswise — BOSTON – Scientists at Dana-Farber Cancer Institute and Mass General Cancer Center have created molecular ON-OFF switches to regulate the activity of CAR T cells, a potent form of cell-based immunotherapy that has had dramatic success in treating some advanced cancers,…

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