Health
SARS‐CoV‐2 infection and paediatric endocrine disorders: Risks and management considerations – Wiley
The SARS-CoV-2 virus has multiple potential pathophysiologic interconnections with endocrine systems. In this review, we present the effects of SARS-CoV-2 infection…
1 INTRODUCTION
Coronavirus disease 19 (COVID-19) is caused by the SARS-CoV-2 virus, the seventh coronavirus identified as causing disease in humans. Angiotensin-converting enzyme 2 (ACE2) is considered to be the primary receptor mediating SARS-CoV-2 infection.1 Binding of SARS-CoV-2 to ACE2 triggers a cascade leading to activation of the NF-kB pathway, increasing proinflammatory cytokines and chemokines to very high levels, leading to the development of acute respiratory distress syndrome (ARDS)…
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