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SARS-CoV-2 RNA Viral Load Dynamics and Duration of Shedding – Infectious Disease Advisor

Despite prolonged RNA shedding in SARS-CoV-2 patients, viable virus appears to be short lived, but high titers are detected early in disease course.

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According to a meta-analysis of studies regarding coronavirus viral kinetics, SARS-CoV-2 RNA shedding can be prolonged but the duration of viable virus is relatively short. The results of this review of studies reporting on SARS-CoV-2, SARS-CoV, or MERS-CoV infection were published in The Lancet Microbe.
Investigators analyzed 79 SARS-CoV-2 studies with 5340 individuals, 8 SARS-CoV studies with 1858 individuals, and 11 MERS-CoV studies with 799 individuals.
Of the 79 studies about SARS-CoV-2, 61…

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