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Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia – The Lancet

The heterologous rAd26 and rAd5 vector-based COVID-19 vaccine has a good safety profile
and induced strong humoral and cellular immune responses in participants. Further
investigation is needed of the effectiveness of this vaccine for prevention of COVID-19.

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