Science
Safeguarding of key DNA sensor in innate immune system – Science Daily
New research reveals in detail how the nucleosomes inside our cells block cGAS from unintentionally triggering the body’s innate immune response to our own DNA.
UNC-Chapel Hill researchers have, for the first time, determined the high-resolution structure of a key DNA-sensing protein in the innate immune system called cGAS while it is bound to the nucleosome — the all-important unit of DNA packaging inside a cell’s nucleus.This research, published in Science, reveals in detail how the nucleosomes inside our cells block cGAS from unintentionally triggering the body’s innate immune response to our own DNA. The work was led by Qi Zhang, PhD, associate pro…
-
General16 hours agoAustralian celebrity chef Peter Russell-Clarke dies aged 89
-
General18 hours agoBack-to-back rate cuts tipped when Reserve Bank meets
-
Noosa News18 hours agoWoman left with significant arm injuries in lion attack at Darling Downs Zoo in Queensland
-
Business21 hours agoThese ASX 200 shares could rise 55% to 65%