‘Rewiring’ metabolism in insulin-producing cells may aid Type 2 diabetes treatment – Newswise

Newswise — MADISON, Wis. — Researchers have discovered a previously unknown way that pancreatic cells decide how much insulin to secrete. It could provide a promising new target to develop drugs for boosting insulin production in people with Type 2 diabetes.
In a pair of papersrecently published in Cell Metabolism, scientists from the University of Wisconsin–Madison and their colleagues point to an overlooked enzyme known as pyruvate kinase as the primary way pancreatic beta cells sense sugar levels…

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