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Researchers make ‘exciting first step’ to better understanding development and treatment of autism – BioPharma-Reporter.com

US based scientists have hit upon a method to efficiently identify potential biological mechanisms underlying autism spectrum disorder (ASD); the Harvard and MIT…

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The authors of a paper, published in the journal Science, in an attempt to study the function of genes implicated in autism spectrum disorders (ASDs), applied a gene-editing and single-cellsequencing system, Perturb-Seq, to knock out 35 ASD candidate genes in multiple mice embryos. 
They described how the Perturb-Seq method they developed can investigate the function of many different genes in many different cell types at once. 
Directing the large-scale method to the study of dozens of genes that…

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