Health
Researchers develop innovative biosensor that can detect and quantitate SARS-CoV-2 infection – News-Medical.net
Researchers have generated protease-activatable fluorescent and luminescent biosensors for SARS-CoV-2 MPro (main protease) and PLPro (papain-like protease) activity,…
The actions of a drug or a molecular target in vitro often do not translated in a cellular or in vivo context. Membrane permeability, off-target effects, and cytotoxicity are some of the factors that may contribute to this difference. This is a huge bottleneck in the effort to urgently identify novel antiviral therapies, especially in the wake of the coronavirus disease 2019 (COVID-19) pandemic.
The etiological agent of COVID-19 is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It…
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