Researchers assess molecular basis of SARS-CoV-2 severity and poor outcomes in lung disease – News-Medical.Net

Researchers from the United States and the United Kingdom have shown that chronic lung disease is a risk factor for more severe COVID-19 and worse outcomes. A recent study published on the preprint server bioRxiv* in October 2020 shows that in patients with chronic lung disease, the pattern of gene expression in the different types of cell changes such that the lung epithelium is prepared to tackle SARS-CoV-2 infection. Also, the altered gene programs have an impact on the immune response.
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