Health
Research shows how remdesivir inhibits SARS-CoV-2 replication – News-Medical.Net
In a recent bioRxiv preprint, a research team from Germany, Goran Kokic et al. study the molecular mechanism of remdesivir-induced stalling of RdRp – using synthetic…
Amidst the frantic global search for a vaccine to inhibit SARS-CoV-2 or a drug to treat coronavirus 2019 (COVID-19), remdesivir has been recently approved by the U.S. FDA to treat COVID-19 patients.
The causative agent of COVID-19, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has exhibited a positive response to this nucleoside analog drug.
The virus uses an RNA-dependent RNA polymerase (RdRp) to replicate. The active form of remdesivir inhibits the RdRp and exhibits antiviral…
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