Health
Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension – News-Medical.Net
A new study, appearing as a preprint on the medRxiv* server, demonstrates the protective effect of drugs in older COVID-19 patients with hypertension.
The ongoing coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The virus binds to the target host cell via the angiotensin-converting enzyme 2 (ACE2). This receptor is also part of the renin-angiotensin system (RAS) that regulates the cardiovascular system and renal function.
ACE2 is a RAS inhibitor. Some animal studies show that among the RAS inhibitors (RASIs), some may increase ACE2 levels, thus promoting viral entry into human…
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